![]() Ginseng roots have been used for over 2,000 years in many Asian countries. Further studies with a higher dosage of ginseng, a larger sample size, and a longer follow-up period are necessary to confirm the clinical efficacy of Korean red ginseng. Our results suggest that the decreased latency in ERP is associated with improved cognitive function. ![]() After 2 wk, significant decreases were observed in the P300 latencies at Cz ( p=0.008), C3 ( p=0.005), C4 ( p=0.002), and C mean ( p=0.003) in the red ginseng group. In the event-related potential test, the C3 latency of the red ginseng group tended to decrease during the study period ( p=0.005). There were no significant differences in the Vienna test system scores between the red ginseng group and the placebo group. All of the subjects were analyzed with the Vienna test system and a P300 event-related potential (ERP) test. There were 8 subjects in the red ginseng group and 7 subjects in the placebo group. The subjects were randomly assigned to receive a daily dose of 4,500 mg red ginseng or placebo for a 2-week trial. A total of 15 healthy young males with no psychiatric or cognitive problems were selected based on an interview with a board-certified psychiatrist. The purpose of this study was to investigate the effect of Korean red ginseng on cognitive performance in humans. Ginseng has a long history of use for health enhancement, and there is some evidence from animal studies that it has a beneficial effect on cognitive performance.
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